Milestone Scientific Launches FDA-Cleared Single Tooth Anesthesia (STA(TM)) System During Chicago Midwinter Meeting

Milestone
Scientific, Inc. (OTC Bulletin Board: MLSS), a world leader in computer
controlled local anesthetic delivery, will officially unveil its highly
anticipated Single Tooth Anesthesia (STA(TM)) System during this year's
Chicago Dental Society Midwinter Meeting. Milestone will be conducting
demonstrations of the STA System at booth # 2206.


The FDA-cleared STA System is comprised of a computer-controlled drive
unit and a single-use disposable handpiece/needle assembly. It provides
newly-patented real-time visual and audible feedback and verbal
announcements via Milestone Scientific's patented CompuFlo(TM) with Dynamic
Pressure Sensing (DPS(TM)) technology, thus taking the guesswork out of the
administration of anesthetic.



Specifically, the STA System enables the dental professional to
precisely administer an intraligementary injection to anesthetize a single
tooth in only one to two minutes, rather than administering a mandibular
block that anesthetizes an entire quadrant. The STA Intraligamentary
injection has an immediate onset, whereas the typical block injection can
take 8 to 12 minutes before a dentist can start treatment. In addition, the
STA intraligementary injection last as long as a traditional infiltration
or mandibular block. All of this is accomplished with a technology that has
been clinically proven to provide a pain-free injection.



Using 4% Articaine Hydrochloride 1:200,000 local anesthetic solution.



Using the innovative CompuFlo with DPS technology, the STA System
informs the clinician of the exact location of the needle point between the
tooth and bone to directly target the periodontal ligament in order to
comfortably anesthetize a single tooth without causing collateral numbing
of the cheek, lips and tongue or histological damage commonly associated
with the traditional PDL injection.



Moreover, the STA System has been programmed to measure the precise
"exit pressure of an anesthetic as it is injected into tissues of varying
density. It provides constant information so that the dental professional
is in the optimal location during the entire injection.



Furthermore, unlike traditional syringe injections, the STA System
allows the dental professional to start working immediately after the
injection is administered, resulting in definitive and uninterrupted
treatment saving valuable chair time. It also allows work to be performed
in multiple quadrants and in both arches with ease, precision and
efficiency, thus allowing multiple procedures to be completed in a single
office visit.



The STA System incorporates Milestone's CompuDent(TM) technology which
was introduced in 1998 and marked the first major advancement in local
anesthetic delivery since the syringe was invented more than 150 years ago.
Milestone's STA System is well-positioned to make a significant and
positive impact on the predictability and productivity of the dental
practice while improving the overall patient experience, by eliminating
collateral anesthesia with a pain-free injection.
















Milestone received FDA 510(k) Pre-market Notification acceptance in
August 2006 for the marketing and sale of the STA System and has since
entered into an exclusive United States and Canadian distribution agreement
with Henry Schein, Inc. (Nasdaq: HSIC), the world's largest provider of
healthcare products and services to office-based practitioners in the
combined North American and European markets.



About Milestone Scientific, Inc.



Headquartered in Livingston, New Jersey, Milestone Scientific is
engaged in pioneering proprietary, highly innovative technological
solutions for the medical and dental markets. Central to the Company's IP
platform and product development strategy is its patented CompuFlo(TM)
technology for the improved and painless delivery of local anesthetic.
Specifically, CompuFlo is a computer-controlled, pressure-sensitive
infusion, perfusion, and aspiration technology, which provides real-time
readouts of pressures, fluid densities and flow rates, enabling the
advanced delivery of a wide array of pharmaceutical. The Single Tooth
Anesthesia (STA(TM)) computer-controlled local anesthesia delivery system,
which uses this technology, provides dentists with audible and visual
signals as to in-tissue pressure. Milestone's existing painless injection
systems are currently sold in 25 countries. For more information on these
and other innovative Milestone products, please visit the Company's website
found at milesci.



Safe Harbor Statement: This press release contains forward-looking
statements regarding the timing and financial impact of Milestone's ability
to implement its business plan, expected revenues and future success. These
statements involve a number of risks and uncertainties and are based on
assumptions involving judgments with respect to future economic,
competitive and market conditions and future business decisions, all of
which are difficult or impossible to predict accurately and many of which
are beyond Milestone's control. Some of the important factors that could
cause actual results to differ materially from those indicated by the
forward-looking statements are general economic conditions, failure to
achieve expected revenue growth, changes in our operating expenses, adverse
patent rulings, FDA or legal developments, competitive pressures, changes
in customer and market requirements and standards, and the risk factors
detailed from time to time in Milestone's periodic filings with the
Securities and Exchange Commission, including without limitation,
Milestone's Annual Report on Form 10-KSB for the year ended December 31,
2006. The forward looking-statements in this press release are based upon
management's reasonable belief as of the date hereof. Milestone undertakes
no obligation to revise or update publicly any forward-looking statements
for any reason.


Milestone Scientific, Inc.

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